The expression efficiency of heterologous genes or synthetic artificial genes is often low due to un-optimized codon usage. Computer codon optimization is still unreliable and cannot predict maximum yield. Improving protein solubility is even harder and there is little guidance to follow. General Biosystems has developed advanced gene design algorithms and powerful empirical procedures to achieve the maximum expression level or solubility of a given protein sequence in a specified host.
To meet your needs to the fullest extent, General Biosystems also offers Oligo Synthesis, Gene Synthesis, Molecular Biology and Biosystem Optimization services.